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Oesophagus including oesophagogastric junction (ICD10 C15, C16.0)

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Introduction

This is the data sheet for TNM 9th edition staging of the oesophagus including oesophagogastric junction (ICD10 C15 & C16.0).

For more detailed information regarding TNM staging, please see pages 60-65 of the UICC TNM 9 book.

Stage groupings

Squamous Cell Carcinoma - clinical stage*

Stage Group	T stage	N stage	M stage
Stage 0	Tis	N0	cM0
Stage I	T1	N0, N1	cM0
Stage II	T2	N0, N1	cM0
	T3	N0	cM0
Stage III	T1, T2	N2	cM0
	T3	N1, N2	cM0
Stage IVA	T4a, T4b	N0, N1, N2	cM0
	Any T	N3	cM0
Stage IVB	Any T	Any N	cM1

Squamous Cell Carcinoma - pathological stage*

Stage Group	T stage	N stage	M stage
Stage 0	pTis	pN0	cM0
Stage IA	pT1a	pN0	cM0
Stage IB	pT1b	pN0	cM0
Stage IIA	pT2	pN0	cM0
Stage IIB	pT1	pN1	cM0
	pT3	pN0	cM0
Stage IIIA	pT1	pN2	cM0
	pT2	pN1	cM0
Stage IIIB	PT2	pN2	cM0
	pT3	pN1, pN2	cM0
	pT4a	pN0, pN1	cM0
Stage IVA	pT4a	pN2	pM0
	pT4b	Any pN	cM0
	Any pT	pN3	cM0
Stage IVB	Any T	Any N	pM1

Adenocarcinoma - clinical stage*

Stage Group	T stage	N stage	M stage
Stage 0	Tis	N0	cM0
Stage I	T1	N0	cM0
Stage IIA	T1	N1	cM0
Stage IIB	T2	N0	cM0
Stage III	T2	N1	cM0
	T3, T4a	N0,N1	cM0
Stage IVA	T1-T4a	N2	cM0
	T4b	N0, N1, N2	cM0
	Any T	N3	cM0
Stage IVB	Any T	Any N	cM1

Adenocarcinoma pathological stage*

Stage Group	T stage	N stage	M stage
Stage 0	pTis	pN0	cM0
Stage IA	pT1a	pN0	cM0
Stage IB	pT1b	pN0	cM0
Stage IIA	pT2	pN0	cM0
Stage IIB	pT1	pN1	cM0
	pT3	pN0	cM0
Stage IIIA	pT1	pN2	cM0
	pT2	pN1	cM0
Stage IIIB	pT2	pN2	cM0
	pT3	pN1, pN2	cM0
	pT4a	pN0, pN1	cM0
Stage IVA	pT4a	pN2	cM0
	pT4b	Any pN	cM0
	Any pT	pN3	cM0
Stage IVB	Any pT	Any pN	pM1

Note

*If the T or N category is clinical and the other category is pathological, the clinical stage should be used, unless the M category is pM1, in which case the pathological stage is used regardless of whether the T and N categories are pathological or clinical: e.g., for squamous cell carcinoma, pT2cN1 Stage as Clinical Stage II.

TNM clinical classification

T - primary tumour

T value	Description
cTX	Primary tumour cannot be assessed
cT0	No evidence of primary tumour
cTis	Carcinoma in situ/high‐grade dysplasia
cT1	Tumour invades lamina propria, muscularis mucosae, or submucosa
	cT1a - Tumour invades lamina propria or muscularis mucosae
	cT1b - Tumour invades submucosa
cT2	Tumour invades muscularis propria
cT3	Tumour invades adventitia including peri-oesophageal fat
cT4	Tumour invades adjacent structures
	cT4a - Tumour invades pleura, pericardium, azygos vein, diaphragm, or peritoneum
	cT4b - Tumour invades other adjacent structures such as aorta, vertebral body, or trachea

N - regional lymph nodes

N value	Description
cNX	Regional lymph nodes cannot be assessed
cN0	No regional lymph node metastasis
cN1	Metastasis in 1 to 2 regional lymph nodes
cN2	Metastasis in 3 to 6 regional lymph nodes
cN3	Metastasis in 7 or more regional lymph nodes

M - distant metastasis

M value	Description
M0	No distant metastasis
M1	Distant Metastasis

TNM pathological classification

The pT and pN categories correspond to the cT and cN categories as per above.

pN value	Description
pN0	Histological examination of a regional lymphadenectomy specimen will ordinarily include 7 or more lymph nodes. If the lymph nodes are negative, but the number ordinarily examined is not met, classify as pN0