Part of Cancer staging guidance sheets
Neuroblastoma
Introduction
This is the data sheet for TNM 8th edition staging of neuroblastoma
International neuroblastoma risk group
|
Stage |
Description |
|---|---|
|
L1 |
Localised tumour not involving vital structures as defined by the list of image-defined risk factors and confined to one body compartment |
|
L2 |
Locoregional tumour with presence of one or more image-defined risk factors |
|
M |
Distant metastatic disease (except stage MS) |
|
MS |
Metastatic disease in children younger than 18 months with metastases confined to skin, liver, and/or bone marrow |
Image-defined risk factors (IDRFS) in neuroblastic tumours
|
Ipsilateral tumour extension within two body compartments |
Neck-chest, chest-abdomen, abdomen-pelvis |
|---|---|
|
Neck |
Tumour encasing carotid and/or vertebral artery and/or internal jugular vein Tumour extending to base of skull Tumour compressing the trachea |
|
Cervico-thoracic junction |
Tumour encasing brachial plexus roots Tumour encasing subclavian vessels and/or vertebral and/or carotid artery Tumour compressing the trachea |
|
Thorax |
Tumour encasing the aorta and/or major branches Tumour compressing the trachea and/or principal bronchi Lower mediastinal tumour, infiltrating the costo-vertebral junction between T9 and T12 |
|
Thoraco-abdominal |
Tumour encasing the aorta and/or vena cava |
|
Abdomen/pelvis |
Tumour infiltrating the porta hepatis and/or the hepatoduodenal ligament Tumour encasing branches of the superior mesenteric artery at the mesenteric root Tumour encasing the origin of the coeliac axis, and/or of the superior mesenteric artery Tumour invading one or both renal pedicles Tumour encasing the aorta and/or vena cava Tumour encasing the iliac vessels Pelvic tumour crossing the sciatic notch |
|
Intraspinal tumour extension whatever the location provided that: |
More than one third of the spinal canal in the axial plane is invaded and/or the perimedullary leptomeningeal spaces are not visible and/or the spinal cord signal is abnormal |
|
Infiltration of adjacent organs/structures |
Pericardium, diaphragm, kidney, liver, duodeno-pancreatic block, and mesentery |
|
Conditions to be recorded, but not considered IDRFs |
Multifocal primary tumours Pleural effusion, with or without malignant cells Ascites, with or without malignant cells |
Last edited: 14 June 2023 2:12 pm
