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Part of Cancer staging guidance sheets

Soft tissues (ICD10 C15-C26, C34-C37 C38.1-3, C47-C49, C51-C53, C58, C60-C68)

Current Chapter

Current chapter – Soft tissues (ICD10 C15-C26, C34-C37 C38.1-3, C47-C49, C51-C53, C58, C60-C68)


Introduction

This is the data sheet for TNM 9th edition staging of the soft tissues (ICD10 C15-C26, C34-C37, C38.1-3, C47-C49, C51-C53, C58, C60-C68)

For more detailed information regarding TNM staging, please see pages 126-128 of the UICC TNM 9 book.


Stage groupings

Extremity and Superficial Trunk and Retroperitoneum

Stage Group

T stage

N stage

M stage

 

Stage IA

T1

N0

M0

G1, GX low grade

Stage IB

T2, T3, T4

N0

M0

G1, GX low grade

Stage II

T1

N0

M0

G2, G3 high grade

Stage IIIA

T2

N0

M0

G2, G3 high grade

Stage IIIB

T3, T4

N0

M0

G2, G3 high grade

Stage IIIB

Any T

N1*

M0

Any G

Stage IV

Any T

Any N

M1

Any G

* AJCC classifies N1 as stage IV for extremity and superficial trunk

Head and Neck and Thoracic and Abdominal Viscera

There is no stage for soft tissue sarcoma of the head and neck and thoracic and abdominal viscera.


TNM clinical classification

T - primary tumour

T value

Description

cTX

Primary tumour cannot be assessed

cT0

No evidence of primary tumour

Extremity and Superficial Trunk

T value

Description

cT1

Tumour 5 cm or less in greatest dimension

cT2

Tumour more than 5 cm but no more than 10 cm in greatest dimension

cT3

Tumour more than 10 cm but no more than 15 cm in greatest dimension

cT4

Tumour more than 15 cm in greatest dimension

Retroperitoneum

T value

Description

cT1

Tumour 5 cm or less in greatest dimension

cT2

Tumour more than 5 cm but no more than 10 cm in greatest dimension

cT3

Tumour more than 10 cm but no more than 15 cm in greatest dimension

cT4

Tumour more than 15 cm in greatest dimension

Head and Neck

T value

Description

cT1

Tumour 2 cm or less in greatest dimension

cT2

Tumour more than 2 cm but no more than 4 cm in greatest dimension

cT3

Tumour more than 4 cm in greatest dimension

cT4a

Tumour invades the orbit, skull base or dura, central compartment viscera, facial skeleton, and or pterygoid muscles

cT4b

Tumour invades the brain parenchyma, encases the carotid artery, invades prevertebral muscle or involves the central nervous system by perineural spread

Thoracic and Abdominal Viscera

T value

Description

cT1

Tumour confined to a single organ

cT2a

Tumour invades serosa or visceral peritoneum

cT2b

Tumour with microscopic extension beyond the serosa

cT3

Tumour invades another organ or macroscopic extension beyond the serosa

cT4a

Multifocal tumour involving no more than two sites in one organ

cT4b

Multifocal tumour involving more than two sites but not more then 5 sites

cT4c

Multifocal tumour involving more than five sites

N - regional lymph nodes

N value

Description

cNX

Regional lymph nodes cannot be assessed

cN0

No regional lymph node metastasis

cN1

Regional lymph node metastasis

M - distant metastasis

M value

Description

cM0

No distant metastasis

cM1

Distant metastasis


TNM pathological classification

The pT and pN categories correspond to the cT and cN categories as per above.


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Last edited: 16 January 2026 3:55 pm

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  3. Malignant melanoma of upper aerodigestive tract (ICD10 C00-06, C09-14, C30-32)
  4. Pharynx (ICD10 C01, C02.4, C05.1-2, C09, C10.0, C10.2-3, C10.9, C11-13)
  5. Salivary glands (ICD10 C00-C14, C15.0, C30-C33, C41.1)
  6. Oesophagus including oesophagogastric junction (ICD10 C15, C16.0)
  7. Gastrointestinal stromal tumours (ICD10 C15-C20, C48.1-2)
  8. Stomach (ICD10 C16 - excluding C16.0)
  9. Small intestine (ICD10 C17)
  10. Appendix (ICD10 C18.1)
  11. Colon and rectum (ICD10 C18-C20)
  12. Anal and perianal skin (ICD10 C21)
  13. Liver (ICD10 C22.0)
  14. Intrahepatic bile ducts (ICD10 C22.1)
  15. Gallbladder (ICD10 C23)
  16. Distal extrahepatic bile duct (ICD10 C24.0)
  17. Perihilar bile ducts (ICD10 C24.0)
  18. Ampulla of vater (ICD10 C24.1)
  19. Pancreas (ICD10 C25)
  20. Nasal cavity and paranasal sinuses (ICD10 C30.0, C31.0, C31.1)
  21. Larynx (ICD10 C32.0, C32.1, C32.2, C10.1)
  22. Lung (ICD10 C34)
  23. Thymus tumours (ICD10 C37.9)
  24. Soft tissues (ICD10 C15-C26, C34-C37 C38.1-3, C47-C49, C51-C53, C58, C60-C68)
  25. Bone (ICD10 C40, C41)
  26. Melanoma of skin (ICD10 C00.0-2, C00.6, C21.2, C43, C51, C60, C63.2)
  27. Merkel cell carcinoma of skin (ICD10 C00, C44, C51, C60, 63.2, C80)
  28. Skin carcinoma of the head and neck (ICD10 C00.0-2, C00.6, C44.0, C44.2-4)
  29. Carcinoma of skin of the eyelid (ICD10 C44.1)
  30. Carcinoma of skin (excluding eyelid, head and neck, perianal, vulva and penis) (ICD10 C44.5-7, C63.2)
  31. Pleural mesothelioma (ICD10 C38.4)
  32. Breast tumours (ICD10 C50)
  33. Vulva (ICD10 C51)
  34. Cervix uteri (ICD10 C53)
  35. Uterine sarcomas
  36. Uterus - endometrium (ICD10 C54.1, C55)
  37. Ovarian, fallopian tube and primary peritoneal carcinoma (ICD10 C56, C57, C48.1, C48.2)
  38. Gestational trophoblastic neoplasms (ICD10 C58)
  39. Penis tumours (ICD10 C60)
  40. Prostate tumours (ICD10 C61.9)
  41. Testis tumours (ICD10 C62)
  42. Kidney tumours (ICD10 C64)
  43. Renal pelvis and ureter tumours (ICD10 C65 & C66)
  44. Urinary bladder tumours (ICD10 C67)
  45. Urethra tumours (ICD10 C68.0, C61.9)
  46. Carcinoma of conjuctiva (ICD10 C69.0)
  47. Melanoma of conjuctiva (ICD10 C69.0)
  48. Retinoblastoma (ICD10 C69.2)
  49. Melanoma of uvea (ICD10 C69.3-4)
  50. Carcinoma of lacrimal gland (ICD10 C69.5)
  51. Sarcoma of orbit (ICD10 C69.6)
  52. Thyroid gland (ICD10 C73.9)
  53. Adrenal cortex (ICD10 C74.0)
  54. Adrenal medulla and extra-adrenal paraganglia (ICD10 C74.1 C75.5)
  55. Parathyroid gland (ICD10 C75.0)
  56. Unknown primary - cervical nodes (ICD10 C77.0)
  57. Mycosis fungoides or sezary syndrome (ICD10 C84.0 and C84.1)
  58. T and B cutaneous lymphoma (ICD10, C82.6, C84.8, C86.6 and other C83-C86 if primary skin excluding C84.0 C84.1)
  59. Rhabdomyosarcoma (CTYA)
  60. Chronic lymphocytic leukaemia
  61. Hepatoblastoma (CTYA)
  62. Hodgkins and non-hodgkins lymphoma (ICD10 C81-88)
  63. Medulloblastoma
  64. Multiple myeloma
  65. Neuroblastoma
  66. Neuroendocrine tumours of the foregut
  67. Neuroendocrine tumours of the midgut and hindgut
  68. Non-hodgkin lymphoma (children)
  69. Wilms tumour of the kidney