Part of Cancer staging guidance sheets
Gallbladder (ICD10 C23)
Introduction
This is the data sheet for TNM 9th edition staging of the gallbladder (ICD10 C23)
For more detailed information regarding TNM staging, please see pages 87-88 of the UICC TNM 9 book.
Group stagings
|
Stage Group |
T stage |
N stage |
M stage |
|---|---|---|---|
|
Stage 0 |
Tis |
N0 |
M0 |
|
Stage IA |
T1a |
N0 |
M0 |
|
Stage IB |
T1b |
N0 |
M0 |
|
Stage IIA |
T2a |
N0 |
M0 |
|
Stage IIB |
T2b |
N0 |
M0 |
|
Stage IIIA |
T3 |
N0 |
M0 |
|
Stage IIIB |
T1, T2, T3 |
N1 |
M0 |
|
Stage IVA |
T4 |
N0, N1 |
M0 |
|
Stage IVB |
Any T |
N2 |
M0 |
|
|
Any T |
Any N |
M1 |
TNM clinical classification
T - primary tumour
|
T value |
Description |
|---|---|
|
cTX |
Primary tumour cannot be assessed |
|
cT0 |
No evidence of primary tumour |
|
cTis |
Carcinoma in situ |
|
cT1 |
Tumour invades lamina propria or muscular layer cT1a - Tumour invades lamina propria cT1b - Tumour invades muscular layer |
|
cT2 |
Tumour invades perimuscular connective tissue; no extension beyond serosa or into liver cT2a - Tumour invades perimuscular connective tissue on the peritoneal side with no extension to the serosa cT2b - Tumour invades perimuscular connective tissue on the hepatic side with no extension into the liver |
|
cT3 |
Tumour perforates the serosa (visceral peritoneum) and/or directly invades the liver and/or one other adjacent organ or structure, such as stomach, duodenum, colon, pancreas, omentum, extrahepatic bile ducts |
|
cT4 |
Tumour invades main portal vein or hepatic artery or invades two or more extrahepatic organs or structures |
N - regional lymph nodes
|
N value |
Description |
|---|---|
|
cNX |
Regional lymph nodes cannot be assessed |
|
cN0 |
No regional lymph node metastasis |
|
cN1 |
Metastases to 1–3 regional nodes |
|
cN2 |
Metastasis to 4 or more regional nodes |
M - distant metastasis
|
M value |
Description |
|---|---|
|
cM0 |
No distant metastasis |
|
cM1 |
Distant metastasis |
TNM pathological classification
pT - primary tumour
The pT and pN categories correspond to the cT and cN categories as per above.
pN - regional lymph nodes
|
pN value |
Description |
|---|---|
|
pN0 |
Histological examination of a regional lymphadenectomy specimen will ordinarily include 6 or more lymph nodes. If the regional lymph nodes are negative, but the number ordinarily examined is not met, classify as pN0. |
Last edited: 16 January 2026 4:11 pm