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Part of Cancer staging guidance sheets

Melanoma of conjuctiva (ICD10 C69.0)

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Current chapter – Melanoma of conjuctiva (ICD10 C69.0)


Introduction

This is the data sheet for TNM 9th edition staging of melanoma of conjuctiva (ICD10 C69.0).

For more detailed information regarding TNM staging, please see pages 210-212 of the UICC TNM 9 book.


Stage groupings

No stage is at present recommended


TNM clinical classification

T - primary tumour

T value

Description

cTX

Primary tumour cannot be assessed

cT0

No evidence of primary tumour

cTis

Melanoma confined to the conjunctival epithelium (in situ) a

cT1

Melanoma of the bulbar conjunctiva

cT1a - Tumour involves less than or equal to one quadrant b

cT1b - Tumour involves more than one but less than or equal to two quadrants

cT1c - Tumour involves more than two but less than or equal to three quadrants

cT1d - Tumour involves more than three quadrants

cT2

Melanoma of the non‐bulbar conjunctiva involving palpebral, forniceal, and/or caruncular conjunctiva

cT2a - Non‐caruncular tumour involves less than or equal to one quadrant

cT2b - Non‐caruncular tumour involves more than one quadrant

cT2c - Caruncular tumour involves less than or equal to one quadrant of conjunctiva

cT2d - Caruncular tumour involves more than one quadrant of conjunctiva

 

cT3

Tumour with local invasion into:

cT3a - Globe

cT3b - Eyelid

cT3c - Orbit

cT3d - Paranasal sinus, nasolacrimal duct, and/or lacrimal gland

cT4

Tumour invades central nervous system

Note

Melanoma in situ (includes the term primary acquired melanosis) with atypia replacing greater than 75% of the normal epithelial thickness with cytological features of epithelial cells, including abundant cytoplasm, vesicular nuclei, or prominent nucleoli, and/or presence of intraepithelial nest of atypical cells.

Quadrants are defined by clock hour, starting at the limbus (e.g., 6, 9, 12, 3) extending from the central cornea, to and beyond the eyelid margins. This will bisect the caruncle

N - regional lymph nodes

N value

Description

cNX

Regional lymph nodes cannot be assessed

cN0

No regional lymph node metastasis

cN1

Regional lymph node metastasis

M - distant metastasis

M value

Description

cM0

No distant metastasis

cM1

Distant Metastasis


pTNM pathological classification

pT - primary tumour

pT value

Description

pTX

Primary tumour cannot be assessed

pT0

No evidence of primary tumour

pTis

Melanoma confined to the conjunctival epithelium (in situ)*

pT1

Melanoma of the bulbar conjunctiva

pT1a - Tumour 2.0 mm or less in thickness with invasion of the substantia propria

pT1b - Tumour more than 2.0 mm in thickness with invasion of the substantia propria

pT2

Melanoma of the palpebral, forniceal or caruncular conjunctiva

pT2a - Tumour 2.0 mm or less in thickness with invasion of the substantia propria

pT2b - Tumour more than 2.0 mm in thickness with invasion of the substantia propria

pT3

Melanoma invades the eye, eyelid, nasolacrimal system or orbit

pT3a - Invades the globe

pT3b - Invade the eyelid

pT3c - Invades the orbit

pT3d - Invades the paranasal sinus and/or nasolacrimal duct or lacrimal sac

pT4

Melanoma invades central nervous system

Note

* pTis Melanoma in situ (includes the term primary acquired melanosis) with atypia replacing greater than 75 % of the normal epithelial thickness, with cytological features of epithelioid cells, including abundant cytoplasm, vesicular nuclei or prominent nucleoli, and/or presence of intraepithelial nests of atypical cells

pN - regional lymph nodes

The pN categories correspond to the cN categories.


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Last edited: 16 January 2026 3:56 pm

  1. Cancer staging guidance sheets
  2. Oral Cavity and mucosal lip (ICD10 C00.3-5, C02-C06)
  3. Malignant melanoma of upper aerodigestive tract (ICD10 C00-06, C09-14, C30-32)
  4. Pharynx (ICD10 C01, C02.4, C05.1-2, C09, C10.0, C10.2-3, C10.9, C11-13)
  5. Salivary glands (ICD10 C00-C14, C15.0, C30-C33, C41.1)
  6. Oesophagus including oesophagogastric junction (ICD10 C15, C16.0)
  7. Gastrointestinal stromal tumours (ICD10 C15-C20, C48.1-2)
  8. Stomach (ICD10 C16 - excluding C16.0)
  9. Small intestine (ICD10 C17)
  10. Appendix (ICD10 C18.1)
  11. Colon and rectum (ICD10 C18-C20)
  12. Anal and perianal skin (ICD10 C21)
  13. Liver (ICD10 C22.0)
  14. Intrahepatic bile ducts (ICD10 C22.1)
  15. Gallbladder (ICD10 C23)
  16. Distal extrahepatic bile duct (ICD10 C24.0)
  17. Perihilar bile ducts (ICD10 C24.0)
  18. Ampulla of vater (ICD10 C24.1)
  19. Pancreas (ICD10 C25)
  20. Nasal cavity and paranasal sinuses (ICD10 C30.0, C31.0, C31.1)
  21. Larynx (ICD10 C32.0, C32.1, C32.2, C10.1)
  22. Lung (ICD10 C34)
  23. Thymus tumours (ICD10 C37.9)
  24. Soft tissues (ICD10 C15-C26, C34-C37 C38.1-3, C47-C49, C51-C53, C58, C60-C68)
  25. Bone (ICD10 C40, C41)
  26. Melanoma of skin (ICD10 C00.0-2, C00.6, C21.2, C43, C51, C60, C63.2)
  27. Merkel cell carcinoma of skin (ICD10 C00, C44, C51, C60, 63.2, C80)
  28. Skin carcinoma of the head and neck (ICD10 C00.0-2, C00.6, C44.0, C44.2-4)
  29. Carcinoma of skin of the eyelid (ICD10 C44.1)
  30. Carcinoma of skin (excluding eyelid, head and neck, perianal, vulva and penis) (ICD10 C44.5-7, C63.2)
  31. Pleural mesothelioma (ICD10 C38.4)
  32. Breast tumours (ICD10 C50)
  33. Vulva (ICD10 C51)
  34. Cervix uteri (ICD10 C53)
  35. Uterine sarcomas
  36. Uterus - endometrium (ICD10 C54.1, C55)
  37. Ovarian, fallopian tube and primary peritoneal carcinoma (ICD10 C56, C57, C48.1, C48.2)
  38. Gestational trophoblastic neoplasms (ICD10 C58)
  39. Penis tumours (ICD10 C60)
  40. Prostate tumours (ICD10 C61.9)
  41. Testis tumours (ICD10 C62)
  42. Kidney tumours (ICD10 C64)
  43. Renal pelvis and ureter tumours (ICD10 C65 & C66)
  44. Urinary bladder tumours (ICD10 C67)
  45. Urethra tumours (ICD10 C68.0, C61.9)
  46. Carcinoma of conjuctiva (ICD10 C69.0)
  47. Melanoma of conjuctiva (ICD10 C69.0)
  48. Retinoblastoma (ICD10 C69.2)
  49. Melanoma of uvea (ICD10 C69.3-4)
  50. Carcinoma of lacrimal gland (ICD10 C69.5)
  51. Sarcoma of orbit (ICD10 C69.6)
  52. Thyroid gland (ICD10 C73.9)
  53. Adrenal cortex (ICD10 C74.0)
  54. Adrenal medulla and extra-adrenal paraganglia (ICD10 C74.1 C75.5)
  55. Parathyroid gland (ICD10 C75.0)
  56. Unknown primary - cervical nodes (ICD10 C77.0)
  57. Mycosis fungoides or sezary syndrome (ICD10 C84.0 and C84.1)
  58. T and B cutaneous lymphoma (ICD10, C82.6, C84.8, C86.6 and other C83-C86 if primary skin excluding C84.0 C84.1)
  59. Rhabdomyosarcoma (CTYA)
  60. Chronic lymphocytic leukaemia
  61. Hepatoblastoma (CTYA)
  62. Hodgkins and non-hodgkins lymphoma (ICD10 C81-88)
  63. Medulloblastoma
  64. Multiple myeloma
  65. Neuroblastoma
  66. Neuroendocrine tumours of the foregut
  67. Neuroendocrine tumours of the midgut and hindgut
  68. Non-hodgkin lymphoma (children)
  69. Wilms tumour of the kidney